Stability-Indicating HPTLC Method for Simultaneous Estimation of Amoxicillin Trihydrate and Ambroxol Hydrochloride in Bulk and Pharmaceutical Dosage Form
نویسندگان
چکیده
منابع مشابه
Stability-Indicating HPTLC Method for Simultaneous Estimation of Amoxicillin Trihydrate and Ambroxol Hydrochloride in Bulk and Pharmaceutical Dosage Form
Copyright: © 2013 Chitlange SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Stability-Indicating HPTLC Method for Simultaneous Estimation of Amoxicillin Trihydrate and Ambroxol Hydrochloride in Bulk...
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A simple, selective, precise, and stability-indicating high-performance thin-layer chromatographic (HPTLC) method for the analysis of ambroxol hydrochloride both as a bulk drug and in formulations was developed and validated. The method employed HPTLC aluminium plates precoated with silica gel 60F-254 as the stationary phase. The solvent system consisted of methanol-triethylamine (4:6 v/v). The...
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متن کاملValidated Stability−Indicating LC Method for Estimation of Amoxicillin Trihydrate in Pharmaceutical Dosage Forms and Time-Dependent Release Formulations
The objective of this study was to establish a validated stability-indicating LC method for routine analysis of amoxicillin trihydrate in bulk drug samples, different pharmaceutical formulations, and degradation kinetics of the drug under different ICH recommended stress conditions. Chromatographic separation was achieved by a Capacel Pak C18 column with 50:50% v/v methanol-0.02 M phosphate buf...
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ژورنال
عنوان ژورنال: Pharmaceutica Analytica Acta
سال: 2013
ISSN: 2153-2435
DOI: 10.4172/2153-2435.1000261